Angelika Manhart

    ASSISTANT PROFESSOR FOR MATHEMATICAL BIOLOGY

    UNIVERSITY OF VIENNA, AUSTRIA

    Publications

    Preprints/Submitted

• Leech, V., Dalwadi, M. P., & Manhart, A. A dynamical analysis of the alignment mechanism between two interacting cells. bioRxiv, 2024-07 - link to bioRxiv
  
• Lancaster, C., Manhart, A. and Pichaud, F. Coordinating basal surface contraction and cell elongation enables thickening of a  curved epithelium - submitted
  

    Published/Accepted

• V. Leech, F.N. Kenny, S. Marcotti, T.J. Shaw, B.M. Stramer & A. Manhart. Derivation and simulation of a computational model of active cell populations: How overlap avoidance, deformability, cell-cell junctions and cytoskeletal forces affect alignment. PLoS Computational Biology 20.7 (2024): e1011879

• F.N. Kenny et al. Autocrine IL-6 drives cell and extracellular matrix anisotropy in scar fibroblasts. Matrix Biology 123 (2023): 1-16

• H.Z. Ford, A. Manhart, J.R. Chubb, Controlling periodic long-range signalling to drive a morphogenetic transition. eLife (2023) 12:e83796
• P. Degond, A. Manhart, S. Merino-Aceituno, D. Peurichard & L. Sala. How environment affects active particle swarms: a case study. Royal Society Open Science, 9(12), 220791 (2022)
  

• B.D. Karkaria, A. Manhart, A.J.H. Fedorec, C.P. Barnes, Chaos in small microbial communities. PLoS Computational Biology 18 (10) e1010548

• V. Leech, J.W. Hazel, J.C. Gatlin, A.E. Lindsay, A. Manhart, Mathematical modeling accurately predicts the dynamics and scaling of nuclear growth in discrete cytoplasmic volumes. Journal of Theoretical Biology (2021): 110936
  

• P. Aceves-Sanchez, P. Degond, E.E. Keaveny, A. Manhart, S. Merino-Aceituno, D. Peurichard, Large-scale dynamics of self-propelled particles moving through obstacles: model derivation and pattern formation. Bulletin of Mathematical Biology (2020) 82(129)

• S. Hittmeir, L. Kanzler, A. Manhart and C. Schmeiser,Kinetic modelling of colonies of myxobacteria. Kinetic and Related Models (2021) 14(1):1-24 - link to arXiv

• N. Ierushalmi, M. Malik-Garbi, A. Manhart, E. Abu Shah, B. Goode, A. Mogilner and K. Keren, Centering and symmetry breaking in confined contracting actomyosin networks. eLife (2020) e55368
  

• A. Manhart, M. Azevedo, M. Baylies and A. Mogilner Reverse engineering forces responsible for dynamic clustering and spreading of multiple nuclei in developing muscle cells. Molecular Biology of the Cell (2020) mbc-E19

• D. Bhaskar, A. Manhart, J. Milzman, J.T. Nardini, K. Storey, C.M. Topaz, L. Ziegelmeier Analyzing collective motion using machine learning and topology. Chaos (2019) 29(12),123125 - link to arXiv

• A. Manhart, A. Icheva, C. Guerin, T. Klar, R. Boujemaa-Paterski, M. Thery, L. Blanchoin, A. Mogilner, Quantitative regulation of the dynamic steady state of actin networks. eLife (2019) 8:e42413

• S. Windner, A. Manhart, A. Brown, A. Mogilner and M. Baylies, Nuclear scaling is coordinated among individual nuclei in multinucleated muscle fibers. Dev Cell (2019) 49(1), 48-62
  

• A. Manhart, Counter-propagating wave patterns in a swarm model with memory. Journal of Mathematical Biology (2018) https://doi.org/10.1007/s00285-018-1287-x

• A. Manhart, S. Windner, M. Baylies and A. Mogilner, Mechanical positioning of multiple nuclei in muscle cells. PLOS Computational Biology (2018) 14(6):e1006208

• P. Degond, A. Manhart, H. Yu, An age-structured continuum model for myxobacteria (Movie) - Mathematical Models & Methods in Applied Sciences (2018) 28(9):1737–1770
  

• A. Mogilner, A. Manhart, Intracellular fluid mechanics: coupling cytoplasmic flow with active cytoskeletal gel. Review article. Annular Review of Fluid Mechanics (2018) 50:347-370
  

• P. Degond, A. Manhart, H. Yu, Continuum model of nematic alignment of self-propelled particles. Discrete and Continuous Dynamical Systems - B (2017), 22:3379-84

• S. Hirsch, A. Manhart, C. Schmeiser, Mathematical Modeling of Myosin Induced Bistability of Lamellipodial Fragments. Journal of Mathematical Biology (2017) 74(1-2):1-22

• A. Manhart, D. Oelz, C. Schmeiser, N. Sfakianakis, Numerical Treatment of the Filament Based Lamellipodium Model (Movie1, Movie2) - in Modeling Cellular Systems, eds. F. Graw, F. Matthäus, and J. Pahle, Springer, (2017)

• A. Mogilner, A. Manhart, Agent-based modeling in cell biology. Review article. Molecular Biology of the Cell, (2016), 27:3379-84

• A. Manhart, C. Schmeiser, Existence of and decay to equilibrium of the filament end density along the leading edge of the lamellipodium. Journal of Mathematical Biology (2016), 74:169-193

• A. Manhart, D. Oelz, C. Schmeiser , N. Sfakianakis, An extended Filament Based Lamellipodium Model produces various moving cell shapes in the presence of chemotactic signals. Journal of Theoretical Biology, 382 (2015), pp. 244-258 (Movie1, Movie2)

    Past preprints

•  A. Manhart, C. Schmeiser, A kinetic transport model for actin-myosin interaction.     

    Publications related to past internships

• B. Hartl, I. Zeller, A. Manhart, B. Selitsch, C.  Lass-Flörl and B. Willinger, A retrospective assessment of four antigen assays for the detection of invasive candidiasis among high risk hospitalized patients. Mycopathologia (2018) 183(3):513-519

• M. Summerer, J. Horst, G. Erhart, H. Weißensteiner, S. Schönherr, D. Pacher, L. Forer, D. Horst, A. Manhart, B. Horst, T. Sanguansermsri, A. Kloss-Brandstätter, Large-scale mitochondrial DNA analysis in Southeast Asia reveals evolutionary effects of cultural isolation in the multi-ethnic population of Myanmar, BMC Evolutionary Biology (2014), 14:17